Microplastics could raise your risk of a heart attack: Scientists discover tiny fragments inside more than 50% of plaques from clogged arteries

  • Experts found plastic in 58% of patients having procedures to clear major artery
  • Findings raise concerns microplastics increase risk of heart disease and strokes

From the 6.8-mile-deep Mariana Trench to the top of Mount Everest, microplastics have been found almost everyone on Earth.

Now, scientists have discovered the tiny plastic particles inside our clogged arteries.

Researchers from the University of Campania found small pieces of plastic in more than half of patients undergoing procedures to clear a major artery in the neck. 

The findings have raised concerns that microplastics could increase your risk of heart disease, strokes, and death. 

‘Our data will dramatically impact cardiovascular health if confirmed because we are defenceless against plastic pollution,’ said Dr Raffaele Marfella, first author of the study.

Researchers from the University of Campania found small pieces of plastic in more than half of patients undergoing procedures to clear a major artery in the neck

The findings have raised concerns that microplastics could increase your risk of heart disease, strokes, and death (stock image)

The findings have raised concerns that microplastics could increase your risk of heart disease, strokes, and death (stock image)

In the study, the researchers analysed 304 patients who had undergone procedures to clear a major artery in the neck. 

More than half (58 per cent) were found to have microscopic and nanoscopic ‘jagged-edged’ pieces of plastic in the plaque lining the blood vessel. 

This included both polyethylene and polyvinyl chloride. 

‘Polyethylene and polyvinyl chloride, in their various forms, are used in a wide range of applications, including the production of food and cosmetics containers and water pipes,’ the team wrote in their study, published in the New England Journal of Medicine.  

Patients with plastic particles in their carotid artery plaque had a 4.5 times higher risk of experiencing a heart attack or stroke or dying during the next three years, the researchers found after taking individuals’ other risk factors into account.

Those patients also had high levels of inflammatory proteins in their blood that are known to play a role in atherosclerosis and heart failure, the researchers said.

Earlier studies have detected various types of microplastics and nanoplastics in multiple tissues, including the colon, liver, spleen, lymph node tissues and placenta. 

Earlier studies have detected various types of microplastics and nanoplastics in multiple tissues, including the colon, liver, spleen, lymph node tissues and placenta (stock image0

Earlier studies have detected various types of microplastics and nanoplastics in multiple tissues, including the colon, liver, spleen, lymph node tissues and placenta (stock image)

While the new study cannot prove the plastic caused patients’ adverse events, it is the first to link the tiny particles with cardiovascular disease outcomes in humans, Dr Philip Landrigan of Boston College, who was not involved in the study, wrote in an editorial that accompanied the report.

The finding of microplastics and nanoplastics in plaque is ‘a breakthrough discovery,’ Landrigan wrote.

Among the questions it prompts, he said, are whether exposure should be considered a cardiovascular risk factor, and how exposure can be reduced.

In a 2022 report on dietary and inhalation exposure to tiny pieces of plastic, the World Health Organization noted that plastics do not belong in the environment, and that measures should be taken to mitigate exposure.

‘The low cost and convenience of plastics are deceptive,’ Landrigan said. 

‘In fact, they mask great harms, such as the potential contribution by plastics to outcomes associated with atherosclerotic plaque.’ 

WHAT CAN MICROPLASTICS DO TO THE HUMAN BODY IF THEY END UP IN OUR FOOD SUPPLY?

According to an article published in the International Journal of Environmental Research and Public Health, our understanding of the potential human health effects from exposure to microplastics ‘constitutes major knowledge gaps.’ 

Humans can be exposed to plastic particles via consumption of seafood and terrestrial food products, drinking water and via the air. 

However, the level of human exposure, chronic toxic effect concentrations and underlying mechanisms by which microplastics elicit effects are still not well understood enough in order to make a full assessment of the risks to humans.

According to Rachel Adams, a senior lecturer in Biomedical Science at Cardiff Metropolitan University, ingesting microplastics could cause a number of potentially harmful effects, such as: 

  • Inflammation: when inflammation occurs, the body’s white blood cells and the substances they produce protect us from infection. This normally protective immune system can cause damage to tissues. 
  • An immune response to anything recognised as ‘foreign’ to the body: immune responses such as these can cause damage to the body. 
  • Becoming carriers for other toxins that enter the body: microplastics generally repel water and will bind to toxins that don’t dissolve, so microplastics can bind to compounds containing toxic metals such as mercury, and organic pollutants such as some pesticides and chemicals called dioxins, which are known to causes cancer, as well as reproductive and developmental problems. If these microplastics enter the body, toxins can accumulate in fatty tissues. 

Reference

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